Ibuprofen or other NSAIDs and COVID-19

Guidance from the Commission of Human Medicines (CHM) Expert Working Group on coronavirus (COVID-19)

The Commission of Human Medicines (CHM) Expert Working Group on coronavirus (COVID-19) has concluded that there is currently insufficient evidence to establish a link between use of ibuprofen, or other non-steroidal anti-inflammatory drugs (NSAIDs), and susceptibility to contracting COVID-19 or the worsening of its symptoms.  See MHRA update, 14 April 2020.

Key messages:
  • Patients can take paracetamol or ibuprofen when self-medicating for symptoms of COVID-19, such as fever and headache, and should follow NHS advice if they have any questions or if symptoms get worse.
  • Patients should always read the patient information when taking over-the-counter medicines, such as ibuprofen and paracetamol, and follow the instructions on how to take the medicines.
  • Healthcare professionals should consider a patient’s individual risk factors, including any history of cardiovascular and gastrointestinal illness, when prescribing ibuprofen. Additionally, ibuprofen should be used with caution in patients with known renal impairment.
  • The lowest effective dose of ibuprofen should be used for the shortest duration necessary to control symptoms.
  • Patients who have been prescribed NSAIDs as a treatment for a long-term condition, such as arthritis, should keep taking these medicines as normal. Adult patients who take low-dose 75mg aspirin regularly for prevention of heart attacks or for vascular disease should continue to do so.
  • Healthcare professionals, patients and carers should report any suspected side effects from a medicine including those purchased over-the-counter to the Yellow Card Centre Scotland.