Otitis media

Treatment of acute otitis media

Analgesia, no antibiotic treatment (majority resolve in 24 hrs)

Amoxicillin
Amoxicillin 500mg capsules

500mg every 8 hours for 5 days

Amoxicillin 250mg/5ml oral suspension sugar free

500mg every 8 hours for 5 days

If penicillin allergic, prescribe doxycycline

Doxycycline
Doxycycline 100mg capsules

200mg on day 1, then 100mg daily for 5 days treatment in total

For penicillin allergy in pregnancy

Erythromycin
Erythromycin 250mg gastro-resistant tablets

500mg every 6 hours for 5 days

Erythromycin ethyl succinate 250mg/5ml oral suspension sugar free

500mg every 6 hours for 5 days

Prescribing Notes:

  • Antibiotics do not reduce pain in the first 24 hours, and make no difference to the likelihood of a further infection or hearing difficulty.
  • Consider antibiotics if any of the following are present: systemic toxicity, otorrhoea, recurrent ear infection, immunocompromised, debilitated or prolonged illness (more than 2-3 days). In other cases consider withholding prescription or give delayed prescription.

History Notes

06/06/2024

Erythromycin ethyl succinate 500mg/5ml oral suspension sugar free discontinued and removed

15/12/2021

East Region Formulary content agreed.

Treatment of acute otitis media

Analgesia, no antibiotic treatment (60% resolve in 24 hrs).

Amoxicillin
Amoxicillin 250mg capsules

See BNFc for dose, duration 5 days.

Amoxicillin 500mg capsules

See BNFc for dose, duration 5 days.

Amoxicillin 125mg/5ml oral suspension sugar free

See BNFc for dose, duration 5 days.

Amoxicillin 250mg/5ml oral suspension sugar free

See BNFc for dose, duration 5 days.

If penicillin allergic, prescribe clarithromycin.

Clarithromycin
Clarithromycin 250mg tablets

See BNFc for dose, duration 5 days.

Clarithromycin 500mg tablets

See BNFc for dose, duration 5 days.

Clarithromycin 125mg/5ml oral suspension

See BNFc for dose, duration 5 days.

Clarithromycin 250mg/5ml oral suspension

See BNFc for dose, duration 5 days.

Prescribing Notes:

  • Antibiotics do not reduce pain in the first 24 hours and make no difference to the likelihood of a further infection or hearing difficulty.
  • Consider antibiotics if any of the following are present: systemic symptoms, recurrent ear infection, immunocompromised, debilitated or prolonged illness (more than 2-3 days).
  • Consider a delayed prescription (2-3 days), or immediate antibiotics for pain relief for:
    • patients with otorrhoea;
    • patients less than 2 years old with bilateral acute otitis media, bulging membrane.
    • patients with a symptom score >8 where 0 = no symptoms; 1 = a little; 2 = a lot. Symptoms include: fever; tugging ears; crying; irritability; difficulty sleeping; less playful; eating less.
  • Oral antibiotics are recommended for acute otitis media in patients where the affected ear is the only hearing ear and in patients with a cochlear implant.
  • Erythromycin is not indicated for otitis media because it is not effective against Haemophilus influenzae; clarithromycin is the drug of choice for penicillin allergic patients.
  • For more information refer to NICE CKS: Otitis media – acute.

History Notes

15/01/2024

East Region Formulary content agreed.