Wound infections
500mg every 6 hours for 7 days
500mg every 6 hours for 7 days
If allergic to penicillin
200mg on day 1, then 100mg daily for 7 days in total
Prescribing Notes:
- Flucloxacillin has adequate streptococcal cover; therefore it is not necessary to prescribe penicillin in addition, for empirical treatment of non-severe cellulitis. If there has been exposure to river or sea water, discuss treatment with a microbiologist.
- All wounds have potential for bacterial infection and may become colonised but swabs should only be taken if there are clinical signs of infection.
- Prescription of antibiotics should not delay appropriate surgical management e.g. drainage or aspiration of an abscess.
- See also Wound Management section of the formulary.
History Notes
15/12/2021
East Region Formulary content agreed.
Choice of treatment depends upon the extent of infection and sensitivity result for the MRSA isolated from patient.
100mg every 12 hours for 5 days
Prescribing Notes:
- MRSA, like other Staphylococcus aureus strains, may be part of normal colonising flora, for example, on skin, on a leg ulcer, in urine in an asymptomatic catheterised patient. The criteria for treating MRSA are the same as for any other pathogen, i.e. clinical evidence of chest infection, soft tissue infection, or systemic illness in a catheterised patient.
- Check sensitivities, if possible before starting systemic antibiotics.
- Most MRSA locally is sensitive to doxycycline.
- If severe infection or no response to monotherapy after 24-48 hours, seek advice from Microbiology.
History Notes
15/12/2021
East Region Formulary content agreed.
Refer to BNFc for dose and duration.
Refer to BNFc for dose and duration.
Refer to BNFc for dose and duration.
Refer to BNFc for dose and duration.
If allergic to penicillin.
For dose and duration see BNFc.
For dose and duration see BNFc.
For dose and duration see BNFc.
For dose and duration see BNFc.
If penicillin allergic and > 12 years an alternative is doxycycline.
For dose and duration see BNFc.
Prescribing Notes:
- Flucloxacillin has adequate streptococcal cover; therefore it is not necessary to prescribe penicillin in addition, for empirical treatment of non-severe cellulitis. If there has been exposure to river or sea water, discuss treatment with a microbiologist.
- All wounds have potential for bacterial infection and may become colonised but swabs should only be taken if there are clinical signs of infection.
- Prescription of antibiotics should not delay appropriate surgical management e.g. drainage or aspiration of an abscess.
- See also Wound Management section of the formulary.
History Notes
15/01/2024
East Region Formulary content agreed.
Choice of treatment depends upon the extent of infection and sensitivity result for the MRSA isolated from patient.
Prescribing Notes:
- MRSA, like other Staphylococcus aureus strains, may be part of normal colonising flora, for example, on skin, on a leg ulcer, in urine in an asymptomatic catheterised patient. The criteria for treating MRSA are the same as for any other pathogen, i.e. clinical evidence of chest infection, soft tissue infection, or systemic illness in a catheterised patient.
- Check sensitivities, if possible before starting systemic antibiotics.
- If severe infection or no response to monotherapy after 24-48 hours, seek advice from Microbiology.
History Notes
15/01/2024
East Region Formulary content agreed.