Uraemic acidosis

Treatment of acidosis associated with kidney disease

Chronic acidosis due to renal impairment.

Sodium bicarbonate
Sodium bicarbonate 500mg capsules

Dose as per specialist.

Renal tubular acidosis.

Potassium acid tartrate + Potassium bicarbonate
Potassium (potassium 6.5mmol) effervescent tablets BPC 1968

Dose as per specialist.

Prescribing Notes:

  • Sodium bicarbonate is used for chronic acidotic states such as uraemic acidosis or renal tubular acidosis. It should be avoided in respiratory acidosis. The response is unpredictable and must be assessed.
  • Potassium bicarbonate is used for hyperchloraemic acidosis associated with K+ deficiency e.g. renal tubular and gastro-intestinal disorders.

History Notes

20/04/2023

East Region Formulary content agreed.

Treatment of acidosis associated with kidney disease

Chronic acidosis

Sodium bicarbonate
Sodium bicarbonate 500mg capsules

Birth - 23 months: 1-2mmol /kg/day, adjusted according to plasma bicarbonate level.
2 - 18 years: 70mmol/m2/day adjusted according to plasma bicarbonate level.

Prescribing Notes:

  • Sodium bicarbonate is used for chronic acidotic states such as uraemic acidosis or renal tubular acidosis. It should be avoided in respiratory acidosis. The response is unpredictable and must be assessed.
  • Sodium bicarbonate may affect the stability or absorption of other drugs if administered at the same time. If possible allow 1-2 hours before administering other drugs.

History Notes

10/06/2020

Content migrated from LJF website.