Irregular uterine bleeding
Treatment of irregular uterine bleeding (contraception required)
Combined oral contraceptive (see Contraception section).
Prescribing Notes:
- Recommendations for combined oral contraceptives can be found in the Contraception section of the formulary.
- For postmenopausal women, see Menopausal symptoms pathways in the Endocrine chapter of the formulary.
History Notes
18/05/2022
East Region Formulary content agreed.
Treatment of irregular uterine bleeding (contraception not required)
Norethisterone
Norethisterone 5mg tablets
To stop bleeding, 5mg 3 times a day for 10 days. To prevent bleeding, 5mg twice daily to be taken from day 19 to day 26 of each cycle.
Medroxyprogesterone
Medroxyprogesterone 2.5mg tablets
2.5-10mg daily for 5-10 days, repeated for 2 cycles, begin treatment on day 16-21 of cycle.
Medroxyprogesterone 5mg tablets
2.5-10mg daily for 5-10 days, repeated for 2 cycles, begin treatment on day 16-21 of cycle.
Medroxyprogesterone 10mg tablets
2.5-10mg daily for 5-10 days, repeated for 2 cycles, begin treatment on day 16-21 of cycle.
Prescribing Notes:
- For postmenopausal women, see Menopausal symptoms pathways in the Endocrine chapter of the formulary.
- Norethisterone has a higher VTE risk than medroxyprogesterone, see Faculty of Sexual and Reproductive Healthcare for further guidance.
History Notes
18/05/2022
East Region Formulary content agreed.