Uterine fibroids

CKS NICE Fibroids

Treatment of Uterine fibroids – initial management

Prescribing Notes:

  • Refer to national and local gynaecology resources for more information on diagnosis, management, referral criteria and non-pharmacological treatment options for uterine fibroids. Drug treatment options include non-steroidal anti-inflammatory drugs (NSAIDs), tranexamic acid, hormonal contraception, or intrauterine delivery systems. For more information see formulary recommendations for menorrhagia, contraception, or menopausal symptoms.

 

History Notes

21/02/2023

New Pathway agreed ERWG Jan 2023

Treatment of Moderate to Severe Uterine Fibroids – specialist management

Restricted to use in patients who have failed or are unsuitable for conventional therapies (first line treatments), such as tranexamic acid, hormonal contraceptives, and intrauterine delivery systems.

Relugolix + Estradiol + Norethisterone acetate
Ryeqo 40mg/1mg/0.5mg tablets

In adult women of reproductive age, 1 tablet once daily, dose to be taken at around the same time each day, starting within 5 days of the onset of menstrual bleeding, consider discontinuing treatment when patient enters menopause.

Prescribing Notes:

  • The position of specialist treatment in this condition pathway is not intended to guide on place in therapy. The place in therapy is directed by a specialist gynaecologist experienced in the management of the condition, use is in line with relevant local or national guidance.

 

History Notes

21/02/2023

New Pathway agreed ERWG Jan 2023